Epitalon: An Anti-Aging Serum Proven to Work

Epitalon – What is it and how does it work?

Epitalon (a.k.a. epithalon or epithalone) is a synthetically-derived tetrapeptide, meaning that it consists of four amino acid chains. It was discovered by the Russian scientist Professor Vladimir Khavinson, who then conducted epitalon-related research for the next 35 years in both animal and human clinical trials. The results were astounding. For the first time ever, human clinical trials proved beyond doubt that a substance consisted of powerful life extension and anti-aging properties.

Epitalon’s primary role is to increase the natural production of telomerase, a natural enzyme that helps cells reproduce telomeres, which are the protective parts of our DNA. This allows the replication of our DNA so the body can grow new cells and rejuvenate old ones.

Younger people produce a relatively large amount of telomerase and longer telomeres. The longer the telomere strands are, the better cell health and replication they provide. However, as people age, the production of telomerase falls and consequently cell replication and health decline. This is the main reason that people age.

Numerous studies have shown the importance of telomerase production and telomere rejuvenation in fighting the symptoms of aging. In one such study conducted on 913 pairs of twins, the twin with stronger telomerase production looked younger and had better health than his/her twin counterpart. In another study of 38 people who were 100 years or older, the healthiest participants had the strongest and longest telomeres.

As epitalon has been shown to increase the production of telomerase which in turn strengthens and lengthens telomeres, this means that epitalon can play a vital role in decreasing the aging process and thus extending human longevity.

This breakthrough discovery in understanding telomerase production shows that epitalon is the only known substance to increase telomerase production and telomere strand length, which are primary factors in fighting aging.

 

Epitalon – The benefits

As a result of epitalon’s effect on telomerase production, the benefits are unique and far-reaching. Benefits of epitalon include:

  • Increase of human lifespan
  • Significant boosting of energy levels
  • Promotion of deeper sleep
  • Delay and prevention of age-related diseases such as cancer, heart disease and dementia
  • Improvement of skin health and appearance
  • Healing of injured and deteriorating muscle cells

The range of benefits that epitalon provides are immense and cannot be squeezed into a single article, but the following will indicate what research so far has shown epitalon can do. If there is one particular benefit of epitalon, it is that epitalon lets us live longer and healthier.

 

Epitalon – A cancer-preventing peptide

Cancer comes in the form of malignant tumors. Epitalon has been shown to inhibit the growth of cancerous tumors, enabling a longer and healthier life in the future.

Epitalon fights cancer by preventing the occurrence of early-stage tumors. This can be explained by looking at the link between the human pineal gland and cancer. The pineal gland secretes a pineal hormone called melatonin, which is responsible for sleep patterns and numerous other functions. According to studies, there is an inverse relationship between melatonin secretion and malignant tumor growth, and epitalon has been found to activate melatonin secretion and therefore prevent cancer in its initial stages. Specifically, epitalon decalcifies and stimulates the pineal gland, enabling it to increase production of melatonin and prevent the growth of malignant tumors.

 

Epitalon – Promoting normal deep sleep patterns

Epitalon stimulates production of melatonin through its action on the pineal gland, and this is why people taking epitalon have reported better sleep patterns and increased deep sleep, which is essential for the body to repair itself and strengthen the immune system.

 

Epitalon – A powerful antioxidant

Research has shown that epitalon is a powerful antioxidant that eliminates oxygen-free radicals responsible for damaging and killing cells. This process, known as oxidative stress, is the root cause of a wide variety of age-related diseases. It is important to note that the human lifespan is inversely related to the number of oxygen-free radicals in the human body, and epitalon is responsible for slowing down and killing these killer radicals. Since free radicals are the main source of degenerative diseases, eliminating them prevents diseases such as cancer, dementia, Alzheimer’s, muscle and joint pain, heart disease, and more.

 

Epitalon – Increasing human lifespan

The unique makeup of humans is determined by our DNA strands. On the tip of each DNA strand are telomeres, which prevent the loss of vital genetic information that happens each time a cell divides. Every time a cell divides, the telomeres get shorter. The more frequent the cell division, the shorter telomeres become, until they become too short, preventing further cell division, growth, and rejuvenation. Numerous studies have shown that the shortening of telomeres is linked to age-related diseases and is a good predictor of early death.

However, there is an enzyme produced naturally in our body called telomerase (not to be confused with ‘telomeres’) which reverses the process of telomere shortening and degradation. Unfortunately our telomerase production declines significantly as we age.

So, when telomerase production is reactivated, cells can exceed their time limit and continue to divide in a healthy manner, allowing us to live longer. This is exactly what epitalon does. It reactivates the production of telomerase which in turn strengthens and elongates the telomeres in our cell’s DNA strands. This decreases cell death and degeneration, extending the lifespan of our cells and preventing a plethora of age-related diseases.

Early research into epitalon found that people who took epitalon had about a 25% longer life than their non-epitalon counterparts. These early studies triggered further studies which corroborated the initial findings. One of these studies reported that epitalon increased the lifespan of elderly and senile individuals by an incredible 50%.

 

Epitalon – Allowing a longer, healthier life

Through its stimulating action on telomerase production and the pineal gland, epitalon plays an important role in inhibiting cancerous tumor growth, increasing the effectiveness of deep sleep, preventing a wide variety of age-related diseases through its elimination of free radicals, and, most importantly, increasing human lifespan. In addition to all of this, it also promotes improved skin health and gives joint and muscle pain relief, the latter being a very common symptom of aging.

 

Epitalon/Epithalon market availability and dosing

Epitalon was rarely heard of just until a few years ago but it is now available in powder and capsule form, which ensures optimal absorption. Epitalon supplements are marketed under the names ‘Epitalon’ or ‘Epithalon’ or ‘A.G.A.G.’. The recommended adult dosage is from 1 to 50 mg daily (with an average dosage of 2-3mg). For maximum effect, epitalon should be taken on an empty stomach. To date there are no known documented side effects of epitalon.

 

References

  1. Anisimov, V.N., Khavinson, V.K. (2009). The use of peptide bioregulators for cancer prevention: results of 35 years of research experience and perspectives. Voprosy Onkologii [Russia]. 55(3):291-304.
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  3. Christensen, K., Thinggaarda, M., McGue, M., Rexbye, H., Hjelmborg, J.B., Aviv, A., … Vaupel, J.W. (2009). Perceived age as clinically useful biomarker of ageing: cohort study. Bio Medical Journal (online). 339:b5262. Retrieved from: http://www.bmj.com/content/bmj/339/bmj.b5262.full.pdf
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  6. Khavinson, V.K., Bondarev, E., Butyugov, A.A. (2003). Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bulleting of Experimental Builogy and Medicine. 135(6): 590-592. Retrieved from: http://link.springer.com/article/10.1023/A%3A1025493705728
  7. Khavinson, V.K., & Morozov, V. (2003). Peptides of pineal gland and thymus prolong human life. Neuroendocrinology Letters. 24:233-240.
  8. Korkushko, O.V., Khavinson, V.K., Shatilo, V.B., Magdich, L.V. (2004). Effect of peptide preparation epithalamin on circadian rhythm on epiphyseal melatonin-producing function in elderly people. Bulletin of Experimental Biology and Medicine [Russia]. 137(4): 127-146.
  9. Kossoy, G., Anisimov, V.N., Ben-Hur, H., Kossoy, N., Zusman, I. (2006). Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in femal C3H/He mice. In Vivo. 20(2):253-257.
  10. Labunets., I.F., Butenko, G.M., Magdich, L.V., Korkushko, O.V., Khavinson, V.K., Shatilo, V.B. (2004). Effect of epithalamin on circadian relationship between the endocrine function of the thymus and melatonin-producing function of the pineal gland in elderly people. Bulletin of Experimental and Biological Medicine [Russia]. 137(5):617-619.
  11. Terry, D.F., Nolan, V.G., Andersen, S.L., Perls, T.T., Cawthon, R. (2008). Association of longer telomeres with better health in centenarians. The Journals of Gerontology Series A, Biological and Medical Sciences. 63(8): 809-812.
  12. Vanhee, C., Moens, G., Van Hoeck, E., Deconinck, E., De Beer, J.O. (2014). Identification of the small research tetra peptide epitalon, assumed to be a potential treatment for cancer, old age and retinitis pigmentosa in two illegal pharmaceutical preparations. Drug Testing & Analysis. 7(3):259-264. doi: 10.1002/dta.1771

Vinogradova, I.A., Bukalev, A.V., Zabezhinski, M.A., Semenchenko, A.V., Khavinson, V.K., Anisimov, V.N. (2007). Effect of Ala-Glu-Asp-Gly peptide on life span and development of spontaneous tumors in female rats exposed to different illumination regimes. Bulletin of Experimental Biology and Medicine. 144(6):825-830.

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